POLYMORPHISM OF RYR1 GENE, ASSOCIATIONS AND POLYMORPHISM OF ESR GENE WITH REPRODUCTIVE TRAITS OF HYBRID PIGS

Polymorphism of RYR1 gene was studied – ryanodine receptor gene (eng. Ryanodine Receptor 1), which mutation leads to the development of swine stress syndrome, and ESR gene – estrogen receptor gene (eng. Estrogen Receptor), having effect on reproductive traits, in population of hybrid sows of Belarusian Large White  Belarusian Meat (BLW  BM), Belarusian Large White  Yorkshire (BLW  Y) and Landrace  Yorkshire (L  Y) when crossed with boars of Duroc (D) breed and hybrid boars of Duroc  Pietrain (D  P) of German selection. All the tested groups of pigs are monomorphic by RYR1 gene, which indicates absence of species susceptible to malignant hyperthermia in the studied population. By ESR gene, for animals of (BLW  BM)  D and (L  Y)  (D  P) two genotypes were determined: ESR^AA and ESR^AB; and correlation of (BLW  BM)  (D  P) and (BLW  Y)  (D  P) showed all the three genotypes. Also the effect of ESR gene polymorphism on the number of reproductive traits of sows was studied. Positive effect of ESR^B allele was determined with animals of correlations (BLW  BM)  (D  P) and (BLW  Y)  (D  P) on such traits as multiple pregnancy, milkiness, litter weight and piglets weight at weaning in 35 days. However, in the groups of animals not having species of ESR^BB genotype, this trend is not traced clearly. The obtained results can be used for implementation in practical breeding by marker genes that will allow to evaluate the frequency of occurrence of desirable and undesirable alleles and conduct further purposeful selection, which will enhance the resistance of animals to stress and increase their performance.

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